Cycloalkylpiperazines as HIV-1 protease inhibitors: enhanced oral absorption
- 作者B. Moon Kim; Ben E. Evans; Kevin F. Gilbert; Colleen M. Hanifin; Joseph P. Vacca; Stuart R. Michelson; Paul L. Darke; Joan A. Zugay; Emilio A. Emini; William Schleif; Jiunn H. Lin; I.-W. Chen; Kari Vastag; Paul S. Anderson; Joel R. Huff
- 卷第5卷
- 期第22期
- 印刷ISSN0960-894X
- 文件大小287.11KB
- 发表时间1995
- DOI10.1016/0960-894x(95)00461-2
- 页码2707-2712
Stereospecific synthesis of a GS 4104 metabolite: Determination of absolute sterochemistry and influenza neuraminidase inhibitory activityWillard Lew; Paul A. Escarpe; Dirk B. Mendel; David J. Sweeny; Choung U. Kim · 1999
ChemInform Abstract: Stereospecific Synthesis of a GS 4104 Metabolite: Determination of Absolute Stereochemistry and Influenza Neuraminidase Inhibitory Activity.Willard Lew; Paul A. Escarpe; Dirk B. Mendel; David J. Sweeny; Choung U. Kim · 2000
A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activityWillard Lew; Huiwei Wu; Dirk B. Mendel; Paul A. Escarpe; Xiaowu Chen; W.Graeme Laver; Bradford J. Graves; Choung U. Kim · 1998
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ChemInform Abstract: A New Series of C3-Aza Carbocyclic Influenza Neuraminidase Inhibitors: Synthesis and Inhibitory Activity.Willard Lew; Huiwei Wu; Dirk B. Mendel; Paul A. Escarpe; Xiaowu Chen; W. Graeme Laver; Bradford J. Graves; Choung U. Kim · 1999
ChemInform Abstract: Carbocyclic Influenza Neuraminidase Inhibitors Possessing a C3-Cyclic Amine Side Chain: Synthesis and Inhibitory Activity.Willard Lew; Huiwei Wu; Xiaowu Chen; Bradford J. Graves; Paul A. Escarpe; Holly L. MacArthur; Dirk B. Mendel; Choung U. Kim · 2000