Identification and Initial Structure−Activity Relationships of (
<i>R</i>
)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors

Identification and Initial Structure−Activity Relationships of ( R )-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors

Holladay, Mark W.; Wasicak, James T.; Lin, Nan-Horng; He, Yun; Ryther, Keith B.; Bannon, Anthony W.; Buckley, Michael J.; Kim, David J. B.; Decker, Michael W.; Anderson, David J.; Campbell, Jeffrey E.; Kuntzweiler, Theresa A.; Donnelly-Roberts, Diana L.; Piattoni-Kaplan, Marietta; Briggs, Clark A.; Williams, Michael; Arneric, Stephen P.

期刊名称Journal of Medicinal Chemistry
作者Holladay, Mark W.; Wasicak, James T.; Lin, Nan-Horng; He, Yun; Ryther, Keith B.; Bannon, Anthony W.; Buckley, Michael J.; Kim, David J. B.; Decker, Michael W.; Anderson, David J.; Campbell, Jeffrey E.; Kuntzweiler, Theresa A.; Donnelly-Roberts, Diana L.; Piattoni-Kaplan, Marietta; Briggs, Clark A.; Williams, Michael; Arneric, Stephen P.
卷第41卷
期第4期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小90.52KB
发表时间1998-02
DOI10.1021/jm9706224
页码407-412

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Identification and Initial Structure−Activity Relationships of ( R )-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors