A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure
<i>trans</i>
-5-Oxohexahydropyrrolo[3,2-
<i>b</i>
]pyrroles (Pyrrolidine-
<i>trans</i>
-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium Methodology

A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans -5-Oxohexahydropyrrolo[3,2- b ]pyrroles (Pyrrolidine- trans -lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium Methodology

Macdonald, Simon J. F.; Clarke, Geoffrey D. E.; Dowle, Michael D.; Harrison, Lee A.; Hodgson, Simon T.; Inglis, Graham G. A.; Johnson, Martin R.; Shah, Prit; Upton, Richard J.; Walls, Steven B.

期刊名称The Journal of Organic Chemistry
作者Macdonald, Simon J. F.; Clarke, Geoffrey D. E.; Dowle, Michael D.; Harrison, Lee A.; Hodgson, Simon T.; Inglis, Graham G. A.; Johnson, Martin R.; Shah, Prit; Upton, Richard J.; Walls, Steven B.
卷第64卷
期第14期
印刷ISSN0022-3263
电子ISSN1520-6904
文件大小387.41KB
发表时间1999-07
DOI10.1021/jo990306s
页码5166-5175

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A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans -5-Oxohexahydropyrrolo[3,2- b ]pyrroles (Pyrrolidine- trans -lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium Methodology