Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity

Gregson, Stephen J.; Howard, Philip W.; Hartley, John A.; Brooks, Natalie A.; Adams, Lesley J.; Jenkins, Terence C.; Kelland, Lloyd R.; Thurston, David E.

期刊名称Journal of Medicinal Chemistry
作者Gregson, Stephen J.; Howard, Philip W.; Hartley, John A.; Brooks, Natalie A.; Adams, Lesley J.; Jenkins, Terence C.; Kelland, Lloyd R.; Thurston, David E.
卷第44卷
期第5期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小269.46KB
发表时间2001-03
DOI10.1021/jm001064n
页码737-748

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Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity