Exploring the Role of Bromine at C(10) of (+)-4-[2-[4-(8-Chloro-3,10-dibromo- 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(
<i>R</i>
)-yl)-1-piperidinyl]-2- oxoethyl]-1-piperidinecarboxamide (Sch-66336): The Discovery of Indolocycloheptapyridine Inhibitors of Farnesyl Protein Transferase

Exploring the Role of Bromine at C(10) of (+)-4-[2-[4-(8-Chloro-3,10-dibromo- 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11( R )-yl)-1-piperidinyl]-2- oxoethyl]-1-piperidinecarboxamide (Sch-66336): The Discovery of Indolocycloheptapyridine Inhibitors of Farnesyl Protein Transferase

Taveras, Arthur G.; Aki, Cynthia; Chao, Jianping; Doll, Ronald J.; Lalwani, Tarik; Girijavallabhan, Viyyoor; Strickland, Corey L.; Windsor, William T.; Weber, Patricia; Hollinger, Frank; Snow, Mark; Patton, Robert; Kirschmeier, Paul; James, Linda; Liu, Ming; Nomeir, Amin

期刊名称Journal of Medicinal Chemistry
作者Taveras, Arthur G.; Aki, Cynthia; Chao, Jianping; Doll, Ronald J.; Lalwani, Tarik; Girijavallabhan, Viyyoor; Strickland, Corey L.; Windsor, William T.; Weber, Patricia; Hollinger, Frank; Snow, Mark; Patton, Robert; Kirschmeier, Paul; James, Linda; Liu, Ming; Nomeir, Amin
卷第45卷
期第18期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小280.75KB
发表时间2002-08
DOI10.1021/jm010463v
页码3854-3864

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Exploring the Role of Bromine at C(10) of (+)-4-[2-[4-(8-Chloro-3,10-dibromo- 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11( R )-yl)-1-piperidinyl]-2- oxoethyl]-1-piperidinecarboxamide (Sch-66336): The Discovery of Indolocycloheptapyridine Inhibitors of Farnesyl Protein Transferase