Structure-based Drug Design of Pyrrolidine-1, 2-dicarboxamides as a Novel Series of Orally Bioavailable Factor Xa Inhibitors

Chad A. Van Huis; Christopher F. Bigge; Agustin Casimiro-Garcia; Wayne L. Cody; Danette A. Dudley; Kevin J. Filipski; Ronald J. Heemstra; Jeffrey T. Kohrt; Lakshmi S. Narasimhan; Robert P. Schaum; Erli Zhang; John W. Bryant; Staci Haarer; Nancy Janiczek; Robert J. Leadley Jr; Thomas McClanahan; J. Thomas Peterson; Kathleen M. Welch; Jeremy J. Edmunds

作者Chad A. Van Huis; Christopher F. Bigge; Agustin Casimiro-Garcia; Wayne L. Cody; Danette A. Dudley; Kevin J. Filipski; Ronald J. Heemstra; Jeffrey T. Kohrt; Lakshmi S. Narasimhan; Robert P. Schaum; Erli Zhang; John W. Bryant; Staci Haarer; Nancy Janiczek; Robert J. Leadley Jr; Thomas McClanahan; J. Thomas Peterson; Kathleen M. Welch; Jeremy J. Edmunds
卷第69卷
期第6期
印刷ISSN1747-0277
电子ISSN1747-0285
文件大小669.83KB
发表时间2007
DOI10.1111/j.1747-0285.2007.00520.x
页码444-450

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Structure-based Drug Design of Pyrrolidine-1, 2-dicarboxamides as a Novel Series of Orally Bioavailable Factor Xa Inhibitors