Indole Cytosolic Phospholipase A
<sub/>2</sub>
α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1
<i>H</i>
-indol-3-yl]propyl}benzoic Acid, Efipladib

Indole Cytosolic Phospholipase A ₂ α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1 H -indol-3-yl]propyl}benzoic Acid, Efipladib

McKew, John C.; Lee, Katherine L.; Shen, Marina W. H.; Thakker, Paresh; Foley, Megan A.; Behnke, Mark L.; Hu, Baihua; Sum, Fuk-Wah; Tam, Steve; Hu, Yonghan; Chen, Lihren; Kirincich, Steven J.; Michalak, Ronald; Thomason, Jennifer; Ipek, Manus; Wu, Kun; Wooder, Lane; Ramarao, Manjunath K.; Murphy, Elizabeth A.; Goodwin, Debra G.; Albert, Leo; Xu, Xin; Donahue, Frances; Ku, M. Sherry; Keith, James; Nickerson-Nutter, Cheryl L.; Abraham, William M.; Williams, Cara; Hegen, Martin; Clark, James D.

期刊名称Journal of Medicinal Chemistry
作者McKew, John C.; Lee, Katherine L.; Shen, Marina W. H.; Thakker, Paresh; Foley, Megan A.; Behnke, Mark L.; Hu, Baihua; Sum, Fuk-Wah; Tam, Steve; Hu, Yonghan; Chen, Lihren; Kirincich, Steven J.; Michalak, Ronald; Thomason, Jennifer; Ipek, Manus; Wu, Kun; Wooder, Lane; Ramarao, Manjunath K.; Murphy, Elizabeth A.; Goodwin, Debra G.; Albert, Leo; Xu, Xin; Donahue, Frances; Ku, M. Sherry; Keith, James; Nickerson-Nutter, Cheryl L.; Abraham, William M.; Williams, Cara; Hegen, Martin; Clark, James D.
卷第51卷
期第12期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小781.92KB
发表时间2008-06
DOI10.1021/jm701467e
页码3388-3413

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Indole Cytosolic Phospholipase A 2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1 H -indol-3-yl]propyl}benzoic Acid, Efipladib

Indole Cytosolic Phospholipase A ₂ α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1 H -indol-3-yl]propyl}benzoic Acid, Efipladib