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Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors

Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors

Dafydd R. Owen; John K. Walker; E. Jon Jacobsen; John N. Freskos; Robert O. Hughes; David L. Brown; Andrew S. Bell; David G. Brown; Christopher Phillips; Brent V. Mischke; John M. Molyneaux; Yvette M. Fobian; Steve E. Heasley; Joseph B. Moon; William C. Stallings; D. Joseph Rogier; David N.A. Fox; Michael J. Palmer; Tracy Ringer; Margarita Rodriquez-Lens; Jerry W. Cubbage; Radhika M. Blevis-Bal; Alan G. Benson; Brad A. Acker; Todd M. Maddux; Michael B. Tollefson; Brian R. Bond; Alan MacInnes; Yung Yu
  • 作者Dafydd R. Owen; John K. Walker; E. Jon Jacobsen; John N. Freskos; Robert O. Hughes; David L. Brown; Andrew S. Bell; David G. Brown; Christopher Phillips; Brent V. Mischke; John M. Molyneaux; Yvette M. Fobian; Steve E. Heasley; Joseph B. Moon; William C. Stallings; D. Joseph Rogier; David N.A. Fox; Michael J. Palmer; Tracy Ringer; Margarita Rodriquez-Lens; Jerry W. Cubbage; Radhika M. Blevis-Bal; Alan G. Benson; Brad A. Acker; Todd M. Maddux; Michael B. Tollefson; Brian R. Bond; Alan MacInnes; Yung Yu
  • 卷第19卷
  • 期第15期
  • 印刷ISSN0960-894X
  • 文件大小3193.98KB
  • 发表时间2009
  • DOI10.1016/j.bmcl.2009.06.012
  • 页码4088-4091
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