The Relative Activity of "Function Sparing" HIV-1 Entry Inhibitors on Viral Entry and CCR5 Internalization: Is Allosteric Functional Selectivity a Valuable Therapeutic Property?

Muniz-Medina, V. M.; Jones, S.; Maglich, J. M.; Galardi, C.; Hollingsworth, R. E.; Kazmierski, W. M.; Ferris, R. G.; Edelstein, M. P.; Chiswell, K. E.; Kenakin, T. P.

期刊名称Molecular Pharmacology
作者Muniz-Medina, V. M.; Jones, S.; Maglich, J. M.; Galardi, C.; Hollingsworth, R. E.; Kazmierski, W. M.; Ferris, R. G.; Edelstein, M. P.; Chiswell, K. E.; Kenakin, T. P.
卷第75卷
期第3期
印刷ISSN0026-895X
文件大小402.58KB
发表时间2009-03-01
DOI10.1124/mol.108.052555
页码490-501

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The Relative Activity of "Function Sparing" HIV-1 Entry Inhibitors on Viral Entry and CCR5 Internalization: Is Allosteric Functional Selectivity a Valuable Therapeutic Property?