Removal of Sphingosine 1-Phosphate Receptor-3 (S1P
<sub/>3</sub>
) Agonism is Essential, But Inadequate to Obtain Immunomodulating 2-Aminopropane-1,3-diol S1P
<sub/>1</sub>
Agonists with Reduced Effect on Heart Rate

Removal of Sphingosine 1-Phosphate Receptor-3 (S1P ₃ ) Agonism is Essential, But Inadequate to Obtain Immunomodulating 2-Aminopropane-1,3-diol S1P ₁ Agonists with Reduced Effect on Heart Rate

Hamada, Maiko; Nakamura, Mitsuharu; Kiuchi, Masatoshi; Marukawa, Kaoru; Tomatsu, Ayumi; Shimano, Kyoko; Sato, Noriko; Sugahara, Kunio; Asayama, Mahoko; Takagi, Kan; Adachi, Kunitomo

期刊名称Journal of Medicinal Chemistry
作者Hamada, Maiko; Nakamura, Mitsuharu; Kiuchi, Masatoshi; Marukawa, Kaoru; Tomatsu, Ayumi; Shimano, Kyoko; Sato, Noriko; Sugahara, Kunio; Asayama, Mahoko; Takagi, Kan; Adachi, Kunitomo
卷第53卷
期第8期
印刷ISSN0022-2623
电子ISSN1520-4804
文件大小1179.41KB
发表时间2010-04-22
DOI10.1021/jm901776q
页码3154-3168

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Removal of Sphingosine 1-Phosphate Receptor-3 (S1P 3 ) Agonism is Essential, But Inadequate to Obtain Immunomodulating 2-Aminopropane-1,3-diol S1P 1 Agonists with Reduced Effect on Heart Rate

Removal of Sphingosine 1-Phosphate Receptor-3 (S1P ₃ ) Agonism is Essential, But Inadequate to Obtain Immunomodulating 2-Aminopropane-1,3-diol S1P ₁ Agonists with Reduced Effect on Heart Rate