Benzoxazolinone aryl sulfonamides as potent, selective Na v 1.7 inhibitors with in vivo efficacy in a preclinical pain model

Pero, Joseph E.; Rossi, Michael A.; Lehman, Hannah D.G.F.; Kelly, Michael J.; Mulhearn, James J.; Wolkenberg, Scott E.; Cato, Matthew J.; Clements, Michelle K.; Daley, Christopher J.; Filzen, Tracey; Finger, Eleftheria N.; Gregan, Yun; Henze, Darrell A.; Jovanovska, Aneta; Klein, Rebecca; Kraus, Richard L.; Li, Yuxing; Liang, Annie; Majercak, John M.; Panigel, Jacqueline; Urban, Mark O.; Wang, Jixin; Wang, Ying-Hong; Houghton, Andrea K.; Layton, Mark E.

期刊名称Bioorganic & Medicinal Chemistry Letters
作者Pero, Joseph E.; Rossi, Michael A.; Lehman, Hannah D.G.F.; Kelly, Michael J.; Mulhearn, James J.; Wolkenberg, Scott E.; Cato, Matthew J.; Clements, Michelle K.; Daley, Christopher J.; Filzen, Tracey; Finger, Eleftheria N.; Gregan, Yun; Henze, Darrell A.; Jovanovska, Aneta; Klein, Rebecca; Kraus, Richard L.; Li, Yuxing; Liang, Annie; Majercak, John M.; Panigel, Jacqueline; Urban, Mark O.; Wang, Jixin; Wang, Ying-Hong; Houghton, Andrea K.; Layton, Mark E.
印刷ISSN0960-894X
文件大小424.69KB
发表时间2017-4
DOI10.1016/j.bmcl.2017.04.040

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Benzoxazolinone aryl sulfonamides as potent, selective Na v 1.7 inhibitors with in vivo efficacy in a preclinical pain model