Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit
<i>Trypanosoma brucei</i>
Pteridine Reductase in Support of Early-Stage Drug Discovery

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

Linciano, Pasquale; Dawson, Alice; Pöhner, Ina; Costa, David M.; Sá, Monica S.; Cordeiro-da-Silva, Anabela; Luciani, Rosaria; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Gribbon, Philip; Reinshagen, Jeanette; Wolf, Markus; Behrens, Birte; Hannaert, Véronique; Michels, Paul A. M.; Nerini, Erika; Pozzi, Cecilia; di Pisa, Flavio; Landi, Giacomo; Santarem, Nuno; Ferrari, Stefania; Saxena, Puneet; Lazzari, Sandra; Cannazza, Giuseppe; Freitas-Junior, Lucio H.; Moraes, Carolina B.; Pascoalino, Bruno S.; Alcântara, Laura M.; Bertolacini, Claudia P.; Fontana, Vanessa; Wittig, Ulrike; Müller, Wolfgang; Wade, Rebecca C.; Hunter, William N.; Mangani, Stefano; Costantino, Luca; Costi, Maria P.

期刊名称ACS Omega
作者Linciano, Pasquale; Dawson, Alice; Pöhner, Ina; Costa, David M.; Sá, Monica S.; Cordeiro-da-Silva, Anabela; Luciani, Rosaria; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Gribbon, Philip; Reinshagen, Jeanette; Wolf, Markus; Behrens, Birte; Hannaert, Véronique; Michels, Paul A. M.; Nerini, Erika; Pozzi, Cecilia; di Pisa, Flavio; Landi, Giacomo; Santarem, Nuno; Ferrari, Stefania; Saxena, Puneet; Lazzari, Sandra; Cannazza, Giuseppe; Freitas-Junior, Lucio H.; Moraes, Carolina B.; Pascoalino, Bruno S.; Alcântara, Laura M.; Bertolacini, Claudia P.; Fontana, Vanessa; Wittig, Ulrike; Müller, Wolfgang; Wade, Rebecca C.; Hunter, William N.; Mangani, Stefano; Costantino, Luca; Costi, Maria P.
卷第2卷
期第9期
印刷ISSN2470-1343
电子ISSN2470-1343
文件大小4911.88KB
发表时间2017-09-30
DOI10.1021/acsomega.7b00473
页码5666-5683

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Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery