Derivation of a system-independent Ki for Pgp-mediated digoxin transport from system-dependent IC50 data by accounting for the contribution of additional digoxin transporters.
Chaudhry, Aqsaa; Chung, Git; Lynn, Adam; Yalvigi, Akshata; Brown, Colin; Ellens, Harma; O'Connor, Michael; Lee, Caroline; Bentz, Joe
- 期刊名称Drug Metabolism and Disposition
- 作者Chaudhry, Aqsaa; Chung, Git; Lynn, Adam; Yalvigi, Akshata; Brown, Colin; Ellens, Harma; O'Connor, Michael; Lee, Caroline; Bentz, Joe
- 印刷ISSN0090-9556
- 电子ISSN1521-009X
- 文件大小982.90KB
- 发表时间2018-01-09
- DOI10.1124/dmd.117.075606