CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Mancuso, Renzo; Fryatt, Gemma; Cleal, Madeleine; Obst, Juliane; Pipi, Elena; Monzón-Sandoval, Jimena; Ribe, Elena; Winchester, Laura; Webber, Caleb; Nevado, Alejo; Jacobs, Tom; Austin, Nigel; Theunis, Clara; Grauwen, Karolien; Daniela Ruiz, Eva; Mudher, Amrit; Vicente-Rodriguez, Marta; Parker, Christine A; Simmons, Camilla; Cash, Diana; Richardson, Jill; Bullmore, Edward T; Bhatti, Junaid; Chamberlain, Samuel J; Correia, Marta M; Crofts, Anna L; Dickinson, Amber; Foster, Andrew C; Kitzbichler, Manfred G; Knight, Clare; Lynall, Mary-Ellen; Maurice, Christina; O'Donnell, Ciara; Pointon, Linda J; Hyslop, Peter St George; Turner, Lorinda; Vertes, Petra; Widmer, Barry; Williams, Guy B; Morgan, B Paul; Leckey, Claire A; Morgan, Angharad R; O'Hagan, Caroline; Touchard, Samuel; Cavanagh, Jonathan; Deith, Catherine; Farmer, Scott; McClean, John; McColl, Alison; McPherson, Andrew; Scouller, Paul; Sutherland, Murray; Boddeke, H W G M (Erik); Richardson, Jill C; Khan, Shahid; Murphy, Phil; Parker, Christine A; Patel, Jai; Jones, Declan; de Boer, Peter; Kemp, John; Drevets, Wayne C; Nye, Jeffrey S; Wittenberg, Gayle; Isaac, John; Bhattacharya, Anindya; Carruthers, Nick; Kolb, Hartmuth; Pariante, Carmine M; Turkheimer, Federico; Barker, Gareth J; Byrom, Heidi; Cash, Diana; Cattaneo, Annamaria; Gee, Antony; Hastings, Caitlin; Mariani, Nicole; McLaughlin, Anna; Mondelli, Valeria; Nettis, Maria; Nikkheslat, Naghmeh; Randall, Karen; Sheridan, Hannah; Simmons, Camilla; Singh, Nisha; Loo, Victoria Van; Vicente-Rodriguez, Marta; Wood, Tobias C; Worrell, Courtney; Zajkowska, Zuzanna; Plath, Niels; Egebjerg, Jan; Eriksson, Hans; Gastambide, Francois; Adams, Karen Husted; Jeggo, Ross; Thomsen, Christian; Pederson, Jan Torleif; Campbell, Brian; Möller, Thomas; Nelson, Bob; Zorn, Stevin; O'Connor, Jason; Attenburrow, Mary Jane; Baird, Alison; Benjamin, Jithen; Clare, Stuart; Cowen, Philip; Huang, I-Shu (Dante); Hurley, Samuel; Jones, Helen; Lovestone, Simon; Mada, Francisca; Nevado-Holgado,

期刊名称Brain
作者Mancuso, Renzo; Fryatt, Gemma; Cleal, Madeleine; Obst, Juliane; Pipi, Elena; Monzón-Sandoval, Jimena; Ribe, Elena; Winchester, Laura; Webber, Caleb; Nevado, Alejo; Jacobs, Tom; Austin, Nigel; Theunis, Clara; Grauwen, Karolien; Daniela Ruiz, Eva; Mudher, Amrit; Vicente-Rodriguez, Marta; Parker, Christine A; Simmons, Camilla; Cash, Diana; Richardson, Jill; Bullmore, Edward T; Bhatti, Junaid; Chamberlain, Samuel J; Correia, Marta M; Crofts, Anna L; Dickinson, Amber; Foster, Andrew C; Kitzbichler, Manfred G; Knight, Clare; Lynall, Mary-Ellen; Maurice, Christina; O'Donnell, Ciara; Pointon, Linda J; Hyslop, Peter St George; Turner, Lorinda; Vertes, Petra; Widmer, Barry; Williams, Guy B; Morgan, B Paul; Leckey, Claire A; Morgan, Angharad R; O'Hagan, Caroline; Touchard, Samuel; Cavanagh, Jonathan; Deith, Catherine; Farmer, Scott; McClean, John; McColl, Alison; McPherson, Andrew; Scouller, Paul; Sutherland, Murray; Boddeke, H W G M (Erik); Richardson, Jill C; Khan, Shahid; Murphy, Phil; Parker, Christine A; Patel, Jai; Jones, Declan; de Boer, Peter; Kemp, John; Drevets, Wayne C; Nye, Jeffrey S; Wittenberg, Gayle; Isaac, John; Bhattacharya, Anindya; Carruthers, Nick; Kolb, Hartmuth; Pariante, Carmine M; Turkheimer, Federico; Barker, Gareth J; Byrom, Heidi; Cash, Diana; Cattaneo, Annamaria; Gee, Antony; Hastings, Caitlin; Mariani, Nicole; McLaughlin, Anna; Mondelli, Valeria; Nettis, Maria; Nikkheslat, Naghmeh; Randall, Karen; Sheridan, Hannah; Simmons, Camilla; Singh, Nisha; Loo, Victoria Van; Vicente-Rodriguez, Marta; Wood, Tobias C; Worrell, Courtney; Zajkowska, Zuzanna; Plath, Niels; Egebjerg, Jan; Eriksson, Hans; Gastambide, Francois; Adams, Karen Husted; Jeggo, Ross; Thomsen, Christian; Pederson, Jan Torleif; Campbell, Brian; Möller, Thomas; Nelson, Bob; Zorn, Stevin; O'Connor, Jason; Attenburrow, Mary Jane; Baird, Alison; Benjamin, Jithen; Clare, Stuart; Cowen, Philip; Huang, I-Shu (Dante); Hurley, Samuel; Jones, Helen; Lovestone, Simon; Mada, Francisca; Nevado-Holgado,
印刷ISSN0006-8950
电子ISSN1460-2156
文件大小2279.22KB
发表时间2019-08-26
DOI10.1093/brain/awz241

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice