Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Lin, Kevin H.; Rutter, Justine C.; Xie, Abigail; Pardieu, Bryann; Winn, Emily T.; Bello, Reinaldo Dal; Forget, Antoine; Itzykson, Raphael; Ahn, Yeong-Ran; Dai, Ziwei; Sobhan, Raiyan T.; Anderson, Grace R.; Singleton, Katherine R.; Decker, Amy E.; Winter, Peter S.; Locasale, Jason W.; Crawford, Lorin; Puissant, Alexandre; Wood, Kris C.

期刊名称Nature Genetics
作者Lin, Kevin H.; Rutter, Justine C.; Xie, Abigail; Pardieu, Bryann; Winn, Emily T.; Bello, Reinaldo Dal; Forget, Antoine; Itzykson, Raphael; Ahn, Yeong-Ran; Dai, Ziwei; Sobhan, Raiyan T.; Anderson, Grace R.; Singleton, Katherine R.; Decker, Amy E.; Winter, Peter S.; Locasale, Jason W.; Crawford, Lorin; Puissant, Alexandre; Wood, Kris C.
印刷ISSN1061-4036
电子ISSN1546-1718
文件大小9441.34KB
发表时间2020-3-16
DOI10.1038/s41588-020-0590-9

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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer